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位置: 首页> 品牌> Sigma-Aldrich> (2E)-3-(4′-Hydroxy-3′-tricyclo[3.3.1.13,7]dec-1-yl[1,1′-biphenyl]-4-yl)-2-propenoic acid

ST1926

(2E)-3-(4′-Hydroxy-3′-tricyclo[3.3.1.13,7]dec-1-yl[1,1′-biphenyl]-4-yl)-2-propenoic acid

品牌
Sigma-Aldrich
货号
SML2061
规格纯度
≥98% (HPLC)
价格
1510.44 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
ST1926
ST 1926
Adarotene
(2E)-3-(4′-Hydroxy-3′-tricyclo[3.3.1.13,7]dec-1-yl[1,1′-biphenyl]-4-yl)-2-propenoic acid
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

生化/生理作用

ST1926 is an atypical retinoid that is able to overcome resistance to ATRA. ST1926 appears to induce apoptosis by production of DNA double-strand breaks (DSB) and chromosomal lesions during the S phase of the cell cycle.
ST1926 is considered to be more apoptotic than CD437. It is much effective in mobilizing calcium than CD437. ST1926 repress toll-like receptor 4 (TLR4)/myeloid differentiation factor 88 (MyD88) signal pathway to disable the actions of nuclear factor-κB (NF-κB). It has the ability to repress inflammation response and ROS synthesis in lung epithelial cellsin vitro.

基本信息

经验(实验)分子式 C25H26O3
分子量 374.47
NACRES NA.77

半岛bd体育手机客户端 性质

测定 ≥98% (HPLC)
形式 powder
颜色 white to beige
溶解性 DMSO: 2 mg/mL, clear
储存温度 2-8℃

安全信息

象形图 GHS07
警示用语: Warning
危险声明 H315 - H319
预防措施声明 P302 + P352 - P305 + P351 + P338
危险分类 Eye Irrit. 2 - Skin Irrit. 2
储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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