半岛bd体育手机客户端 说明
应用
SMER3 may be used in cell signaling studies.
包装
5, 25 mg in glass bottle
生化/生理作用
Inhibition of SCFMet30by SMER3 blocks the ubiquitination of Met4 and activates the Met4-containing transcription complex. The induction of MET-genes results in cell cycle arrest and reduced cell proliferation.1
Small molecule enhancer of rapamycin (SMER); specific inhibitor of Ubiquitin E3 ligase.
基本信息
| 经验(实验)分子式 | C11H4N4O2 |
| 分子量 | 224.18 |
| MDL编号 | MFCD00451458 |
| PubChem化学物质编号 | 329824591 |
| NACRES | NA.77 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | yellow |
| 溶解性 | DMSO: ≥30 mg/mL |
| 储存温度 | 2-8℃ |
| SMILES string | O=C1c2ccccc2-c3nc4nonc4nc13 |
| InChI | 1S/C11H4N4O2/c16-9-6-4-2-1-3-5(6)7-8(9)13-11-10(12-7)14-17-15-11/h1-4H |
| InChI key | SFSSAKVWCKFRHE-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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