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位置: 首页> 品牌> Sigma-Aldrich> Sitamaquine tosylate

Sitamaquine tosylate

品牌
Sigma-Aldrich
CAS
1019640-33-5
货号
SML1542
规格纯度
≥98% (HPLC)
价格
1260.64 *本价格含增值税费
促销
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半岛bd体育手机客户端 名称:
1019640-33-5
Sitamaquine tosylate
N-[6-(Diethylamino)hexyl]-6-methoxy-4-methylquinolin-8-amine tosylate
6-Methoxy-8-(6-diethylaminohexylamine)-4-methylquinoline tosylate
WR-6026
N1,N1-Diethyl-N6-(6-methoxy-4-methyl-8-quinolinyl)-1,6-hexanediamine tosylate
NSC 2452
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包装

5, 25 mg in glass bottle

生化/生理作用

Sitamaquine is also known as WR-6026. It is used in the treatment of visceral leishmaniasis.
Sitamaquine is an orally active 8-aminoquinoline analog that exhibit antiplasmodial and antileishmanial activities. Sitamaquine accumulates in Leishmania parasites. Sitamaquine potently inhibits respiratory chain complex II (succinate dehydrogenase), which leads to an apoptosis-like death of Leishmania parasites.

基本信息

经验(实验)分子式 C21H33N3O · C7H8O3S
分子量 515.71
MDL编号 MFCD17392572
PubChem化学物质编号 329825952

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 powder
颜色 white to beige
溶解性 H2O: 15 mg/mL, clear
储存温度 2-8℃
SMILES string CC1=C(C=C(OC)C=C2NCCCCCCN(CC)CC)C2=NC=C1.CC3=CC=C(S(=O)(O)=O)C=C3
InChI 1S/C21H33N3O.C7H8O3S/c1-5-24(6-2)14-10-8-7-9-12-22-20-16-18(25-4)15-19-17(3)11-13-23-21(19)20;1-6-2-4-7(5-3-6)11(8,9)10/h11,13,15-16,22H,5-10,12,14H2,1-4H3;2-5H,1H3,(H,8,9,10)
InChI key LOBPWLFCZDGYKW-UHFFFAOYSA-N

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 3

Sigma-Aldrich

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