N-(2-Bromophenyl)-N′-(7-cyano-1H-benzotriazol-4-yl)urea

SB265610

品牌

Sigma-Aldrich

CAS

211096-49-0

货号

SML0421

包装型号

规格纯度

≥98% (HPLC)

价格

1503.51 元 *本价格含增值税费

促销

数量

- +

半岛bd体育手机客户端名称：

211096-49-0
SB265610
SB 265610
N-(2-Bromophenyl)-N′-(7-cyano-1H-benzotriazol-4-yl)urea
1-(2-Bromophenyl)-3-(4-cyano-1H-benzo[d] [1,2,3]triazol-7-yl)urea

半岛bd体育手机客户端介绍：

半岛bd体育手机客户端说明

应用

SB265610 has been used:

as a cysteine-amino acid-cysteine (CXC)-chemokine receptor type 2 (CXCR2) antagonist to study its effects on the binding of chemokine with G-protein coupled receptors (GPCR)
as a CX-chemokine receptor type 1 (CXCR1) inhibitor to study its effect on the chemotactic activity of chemokines on inflammatory cells
as a CXCR2 antagonist to study its effect on migration of neutrophils to the rat brain

包装

5, 25 mg in glass bottle

生化/生理作用

SB265610 is a potent and selective CXCR2 chemokine receptor antagonist. It has a Kd = 2.5 nM.

特点和优势

This compound is featured on the Chemokine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式	C₁₄H₉BrN₆O
分子量	357.16
MDL编号	MFCD09971124
PubChem化学物质编号	329825416
NACRES	NA.77

半岛bd体育手机客户端性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to light brown
溶解性	DMSO: 15 mg/mL, clear
储存温度	2-8℃
SMILES string	Brc1ccccc1NC(=O)Nc2ccc(C#N)c3nn[nH]c23
InChI	1S/C14H9BrN6O/c15-9-3-1-2-4-10(9)17-14(22)18-11-6-5-8(7-16)12-13(11)20-21-19-12/h1-6H,(H2,17,18,22)(H,19,20,21)
InChI key	SEDUMQWZEOMXSO-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302
危险分类	Acute Tox. 4 Oral
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable