您好,欢迎来到半岛电竞官方网址 ! [ 登录] [ 免费注册]
半岛电竞官方网址
位置: 首页> 品牌> Sigma-Aldrich> N-(6,8-Difluoro-2-methyl-4-quinolinyl)-N′-[4-(dimethylamino)phenyl]urea

SB-408124

品牌
Sigma-Aldrich
CAS
288150-92-5
货号
S2694
规格纯度
≥98% (HPLC), solid
价格
1943 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
288150-92-5
SB-408124
N-(6,8-Difluoro-2-methyl-4-quinolinyl)-N′-[4-(dimethylamino)phenyl]urea
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

SB-408124 was used to block orexin A-mediated cardiovascular effects in rats.It was used to study block the increase of endogenous glucose production mediated by bicuculline in rats.

包装

5, 25 mg in glass bottle

生化/生理作用

SB-408124 blocks the orexin type 1 receptor that stimulates the production of stress hormone in hypothalamus. It blocks orexin A-induced increase in arterial pressure and elevation of heart rate in rats. SB-408124 modulates phrenic nerve activity that is important in respiration.
SB 408124 is an OX1orexin receptor antagonist.

特点和优势

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

法律信息

Sold for research purposes under agreement from GlaxoSmithKline

基本信息

经验(实验)分子式 C19H18F2N4O
分子量 356.37
MDL编号 MFCD06411575
PubChem化学物质编号 329824523
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 solid
颜色 off-white
溶解性 DMSO: >10 mg/mL
创始人 GlaxoSmithKline
储存温度 2-8℃
SMILES string CN(C)c1ccc(NC(=O)Nc2cc(C)nc3c(F)cc(F)cc23)cc1
InChI 1S/C19H18F2N4O/c1-11-8-17(15-9-12(20)10-16(21)18(15)22-11)24-19(26)23-13-4-6-14(7-5-13)25(2)3/h4-10H,1-3H3,(H2,22,23,24,26)
InChI key JTARFZSNUAGHRB-UHFFFAOYSA-N

安全信息

象形图 GHS07
警示用语: Warning
危险声明 H315 - H319 - H335
预防措施声明 P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类 Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官 Respiratory system
储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 dust mask type N95 (US), Eyeshields, Gloves

Sigma-Aldrich

推荐半岛bd体育手机客户端
Baidu
map