半岛bd体育手机客户端 说明
应用
SB-269970 hydrochloride has been used to study the effect of different endotype combination on the activity of the 5-hydroxytryptamine receptor of tall fescue alkaloids. It has also been used to inhibit dopamine receptor signaling, in order to study its role in early hemocyte activation.
SB-269970 was used to study the role of 5-HT7receptors in serotonin-induced hypothermia in rodents.6
包装
5, 25 mg in glass bottle
生化/生理作用
SB-269970 is an anti-psychotic agent that shows high affinity for 5-HT7receptors. It may be effective in treating cognitive disabilities and schizophrenia-like deficits.4SB-269970 desensitizes and decreases the excitatory effects of 5-HT7receptors in rat hippocampus.5
Selective 5-HT7serotonin receptor antagonist.
法律信息
Sold with the permission of GlaxoSmithKline Pharmaceuticals
基本信息
| 经验(实验)分子式 | C18H28N2O3S · HCl |
| 分子量 | 388.95 |
| MDL编号 | MFCD03788020 |
| PubChem化学物质编号 | 24278708 |
| NACRES | NA.77 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 旋光性 | [α]/D 75 to 90°, c = 1.0 in DMSO |
| 储存条件 | desiccated |
| 溶解性 | H2O: 10 mg/mL, clear (warmed to 60 ℃) |
| 储存温度 | 2-8℃ |
| SMILES string | Cl.CC1CCN(CC1)CC[C@H]2CCCN2S(=O)(=O)c3cccc(O)c3 |
| InChI | 1S/C18H28N2O3S.ClH/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18;/h2,5-6,14-16,21H,3-4,7-13H2,1H3;1H/t16-;/m1./s1 |
| InChI key | XQCJOYZLWFNDIO-PKLMIRHRSA-N |
| Gene Information | human ... HTR7(3363) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
