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位置: 首页> 品牌> Sigma-Aldrich> S32826 disodium salt hydrate

S32826 disodium salt hydrate

品牌
Sigma-Aldrich
CAS
1096770-84-1
货号
S1825
规格纯度
≥98% (HPLC)
价格
2486.58 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
1096770-84-1
S32826 disodium salt hydrate
[4-(Tetradecanoylamino)benzyl]phosphonic acid disodium salt hydrate
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

S32826, a potent inhibitor of autotaxin (ATX), may be used to identify and characterize the lyso-phospholipase D (lysoPLD, ATX) involved in bioactive lyso-phosphatidic acid (LPA) formation. S32826 may be used to help determine the role of ATX in malignant cell processes such as tumorigenesis, invasion, and metastases; cardia bifida and atherosclerosis.

包装

5, 25 mg in glass bottle

生化/生理作用

S32826 is a potent inhibitor of autotaxin. Autotaxin is a newly discovered lyso-phospholipase D (lysoPLD). Autotaxin and lyso-phosphatidic acid (LPA) have been associated with early cancer progression and motility of cancer cells as well as with metastasis. Because of localization (adipose tissue), the enzyme might play an important role in diabetes and obesity. Autotaxin might be the only source of LPA. S32826 is the strongest inhibitor of autotaxin reported. The compound shows activity in cellular orex vivomodels.

基本信息

经验(实验)分子式 C21H34NNa2O4P · xH2O
分子量 441.45 (anhydrous basis)
MDL编号 MFCD12912442
PubChem化学物质编号 329824492
NACRES NA.25

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 powder
储存条件 desiccated
颜色 white
溶解性 H2O: ≥10 mg/mL
储存温度 ?20℃
SMILES string [Na+].[Na+].CCCCCCCCCCCCCC(=O)Nc1ccc(CP([O-])([O-])=O)cc1
InChI 1S/C21H36NO4P.2Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-21(23)22-20-16-14-19(15-17-20)18-27(24,25)26;;/h14-17H,2-13,18H2,1H3,(H,22,23)(H2,24,25,26);;/q;2*+1/p-2
InChI key DGRFALMFDGBLCP-UHFFFAOYSA-L

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves, type N95 (US)

Sigma-Aldrich

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