半岛bd体育手机客户端 说明
应用
S15535 has been used as a serotonin 1A receptor (5-HT1A) agonist in zebrafish.
S15535 may be used in histamine 5-HT1A-medaited cell signaling studies.
包装
25 mg in glass bottle
生化/生理作用
S15535, a benzodioxane, is a selective but partial agonist of histamine serotonin 1A (5-HT1A) receptor. It activates presynaptic 5-HT1Areceptors and suppresses the release of hippocampal 5-HT. It acts as an anxiolytic agent and modulates the cholinergic and cognitive function in rodents.
Potent, orally active, partial 5-HT1Areceptor agonist
基本信息
经验(实验)分子式 | C21H24N2O2 |
分子量 | 336.43 |
MDL编号 | MFCD00911672 |
PubChem化学物质编号 | 329824452 |
NACRES | NA.77 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | solid |
颜色 | white |
溶解性 | DMSO: ~6 mg/mL H2O: insoluble |
储存温度 | 2-8℃ |
SMILES string | C1COc2c(O1)cccc2N3CCN(CC3)C4Cc5ccccc5C4 |
InChI | 1S/C21H24N2O2/c1-2-5-17-15-18(14-16(17)4-1)22-8-10-23(11-9-22)19-6-3-7-20-21(19)25-13-12-24-20/h1-7,18H,8-15H2 |
InChI key | QJPPEMXOOWNICQ-UHFFFAOYSA-N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H400 |
预防措施声明 | P273 |
危险分类 | Aquatic Acute 1 |
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves |