半岛bd体育手机客户端 说明
生化/生理作用
Rivaroxaban is an orally active, active site-targeting, highly potent and selective factor Xa (FXa) inhibitor (IC50= 0.7 nM; no activity against thrombin, trypsin, plasmin, FVIIa, FIXa, FXIa, urokinase, or activated protein C up to 20 μM) with good anticoagulant activityin vitro(dose for doubling fibrin formation time = 230/300 nM in human/rat plasma) and antithrombotic efficacyin vivo(ED50= 1 mg/kg i.v. or 5 mg/kg p.o. by rat arteriovenous shunt model).
基本信息
经验(实验)分子式 | C19H18ClN3O5S |
分子量 | 435.88 |
MDL编号 | MFCD11974010 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
旋光性 | [α]/D -34 to -44, c = 0.3 in DMSO |
颜色 | white to beige |
溶解性 | DMSO: 2 mg/mL, clear |
储存温度 | 2-8℃ |
安全信息
象形图 | |
危险声明 | H411 |
预防措施声明 | P273 - P391 - P501 |
危险分类 | Aquatic Chronic 2 |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |