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Rinvanil

品牌
Sigma-Aldrich
CAS
457643-60-6
货号
SML1600
规格纯度
≥98% (HPLC)
价格
1117.23 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
457643-60-6
Rinvanil
(9Z,12R)-12-Hydroxy-N-[(4-hydroxy-3-methoxyphenyl)methyl]-9-octadecenamide
N-Vanillylricinoleamide
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

生化/生理作用

Rinvanil is a Capsaicin analogue that potently activates transient receptor potential vanilloid 1 (TRPV1) channels. Rinvanil induces neuroprotective mild hypothermia in ischemic brain injured mice through TRPV1 activation. Rinvanil exhibits potent anticancer activity in cancer cell lines including cervical (HeLa, CaSKi, ViBo) and leukemia (P388, J774, WEHI-3) cell lines. Rinvanil is not cytotoxic to normal lymphocytes.
TRPV1 (transient receptor potential vanilloid 1) is a capsaicin receptor. It is strongly expressed in sensory neurons and participates in pain perception. In brain, it regulates neuronal function, motor behaviour and neuroinflammation. Capsaicin plays an important role in the activation of TRPV1.

基本信息

经验(实验)分子式 C26H43NO4
分子量 433.62
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 oil
颜色 colorless to yellow
储存温度 2-8℃

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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