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PSEM89S Hydrochloride salt

品牌
Sigma-Aldrich
CAS
1221570-55-3
货号
SML3070
规格纯度
≥98% (HPLC)
价格
978.44 *本价格含增值税费
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半岛bd体育手机客户端 名称:
1221570-55-3
PSEM89S Hydrochloride salt
(S)-2,5-Dimethoxy-N-(quinuclidin-3-yl)benzamide, Hydrochloride salt
PSEM 89S Hydrochloride salt
PSEM-89S Hydrochloride salt
N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxybenzamide Hydrochloride salt
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

生化/生理作用

PSEM89S is a pharmacologically selective effector molecule (PSEM) that acts as a selective agonistin vitroandin vivofor chimeric pharmacologically selective actuator modules (PSAMs) composed of nAChR α7 ligand-binding domain (LBD) with L141F mutation fused to the ion pore domain (IPD) of a ligand-gated ion channel (LGIC), including glycine receptor (PSAML141F-GlyR & PSAML141F/Y115F-GlyR). 5-HT3 (PSAML141F-5-HT3 & PSAML141F/Y115F-5-HT3) and high-conductance 5-HT3 (PSAML141F-5-HT3 HC & PSAML141F/Y115F-5-HT3 HC).

基本信息

经验(实验)分子式 C16H22N2O3· HCl
分子量 326.82

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 powder
储存条件 desiccated
颜色 white to beige
溶解性 DMSO: 2 mg/mL, clear
储存温度 2-8℃
SMILES string O=C(N[C@@H]1CN2CCC1CC2)C3=C(C=CC(OC)=C3)OC.Cl

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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