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位置: 首页> 品牌> Sigma-Aldrich> 5-Methyl-5,8,9,10,11a,12-hexahydro-4H-8,11-ethanopyrido[3′,2′:3,4]diazepino[6,7,1-hi]indole hydrochloride

PSEM308 hydrochloride

5-Methyl-5,8,9,10,11a,12-hexahydro-4H-8,11-ethanopyrido[3′,2′:3,4]diazepino[6,7,1-hi]indole hydrochloride

品牌
Sigma-Aldrich
货号
SML3068
规格纯度
≥98% (HPLC)
价格
1272.2 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
PSEM308 hydrochloride
5-Methyl-5,8,9,10,11a,12-hexahydro-4H-8,11-ethanopyrido[3′,2′:3,4]diazepino[6,7,1-hi]indole hydrochloride
5-Methyl-3,4,14-triazapentacyclo[12.2.2.14,7.02,13.011,19]nonadeca-2,7(19),8,10-tetraene hydrochloride
PSEM 308 hydrochloride
Pharmacologically selective effector molecule 308, hydrochloride
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

生化/生理作用

SEM308 is a pharmacologically selective effector molecule (PSEM) that acts as a selective agonistin vitroandin vivofor chimeric pharmacologically selective actuator modules (PSAMs) composed of nAChR α7 ligand-binding domain (LBD) with L141F or L141F/Y115F mutation fused to the ion pore domain (IPD) of a ligand-gated ion channel (LGIC), including glycine receptor (PSAML141F-GlyR& PSAML141F/Y115F-GlyR) and 5-HT3 (PSAML141F/Y115F-5-HT3).

基本信息

经验(实验)分子式 C17H21N3· HCl
分子量 303.83
MDL编号 MFCD31689250

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 powder
储存条件 desiccated
颜色 white to beige
溶解性 DMSO: 2 mg/mL, clear (warmed)
储存温度 2-8℃
SMILES string CC1CC2=CC=CC3=C2N1N=C(C4CCN5CC4)C5C3.Cl

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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