PS372424 hydrochloride

品牌

Sigma-Aldrich

CAS

914291-61-5

货号

SML0850

包装型号

规格纯度

≥97% (HPLC)

价格

1399.43 元 *本价格含增值税费

促销

数量

- +

半岛bd体育手机客户端名称：

914291-61-5
PS372424 hydrochloride
(S)-N-((S)-1-((Cyclohexylmethyl)amino)-5-guanidino-1-oxopentan-2-yl)-2-(4-oxo-4-phenylbutanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide hydrochloride
(3S)-N-[(1S)-4-[(Aminoiminomethyl)amino]-1-[[(cyclohexylmethyl)amino]carbonyl]butyl]-2-(1,4-dioxo-4-phenylbutyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide hydrochloride

半岛bd体育手机客户端介绍：

半岛bd体育手机客户端说明

包装

5, 25 mg in glass bottle

生化/生理作用

PS372424 is a highly specific agonist of human CXCR3 that potently inhibits the migration of activated T cells toward the chemokine mixture in synovial fluid from patients with active rheumatoid arthritis. PS372424 activated ERK in T cells with a similar potency and kinetic to the natural ligand CXCL11.

基本信息

经验(实验)分子式	C₃₃H₄₄N₆O₄· HCl
分子量	625.20
MDL编号	MFCD28016588
PubChem化学物质编号	329825610
NACRES	NA.77

半岛bd体育手机客户端性质

质量水平	100
测定	≥97% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 20 mg/mL, clear
储存温度	2-8℃
SMILES string	O=C(CCC(C1=CC=CC=C1)=O)N2[C@H](C(N[C@@H](CCCNC(N)=N)C(NCC3CCCCC3)=O)=O)CC4=CC=CC=C4C2.Cl
InChI	1S/C33H44N6O4.ClH/c34-33(35)36-19-9-16-27(31(42)37-21-23-10-3-1-4-11-23)38-32(43)28-20-25-14-7-8-15-26(25)22-39(28)30(41)18-17-29(40)24-12-5-2-6-13-24;/h2,5-8,12-15,23,27-28H,1,3-4,9-11,16-22H2,(H,37,42)(H,38,43)(H4,34,35,36);1H/t27-,28-;/m0./s1
InChI key	XHGSJQNAEULTAR-DHBRAOIWSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable