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位置: 首页> 品牌> Sigma-Aldrich> PF-562,271

PF-562,271

品牌
Sigma-Aldrich
CAS
939791-38-5
货号
PZ0387
规格纯度
≥98% (HPLC)
价格
1729.08 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
939791-38-5
PF-562,271
PF-00562271
N-(3-(((2-((2,3-Dihydro-2-oxo-1H-indol-5-yl)amino)-5- (trifluoromethyl)-4-pyrimidinyl)amino)methyl)-2-pyridinyl)-N-methyl-methanesulfonamide benzenesulfonate
PF 562271
PF-562271
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

PF-562,271 has been used as a focal adhesion kinase (FAK) inhibitor to study its effects on the S100A9-induced tumor cell invasion in prostate cancer cell lines. It has also been used to study its effects on syndecan-1 (SDC-1) knockdown-induced upregulation of early growth regulator 1 (EGR1) in colon cancer cells.

生化/生理作用

PF-562,271 is a potent, ATP-competitive, reversible and selective inhibitor of FAK and Pyk2. PF-562,271 inhibits FAK phosphorylation in vivo.

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.

基本信息

经验(实验)分子式 C21H20F3N7O3S · C6H6O3S
分子量 665.66
MDL编号 MFCD14105612
NACRES NA.77

半岛bd体育手机客户端 性质

测定 ≥98% (HPLC)
形式 powder
manufacturer/tradename Pfizer?
颜色 white to brown
溶解性 DMSO: 2 mg/mL, clear
创始人 Pfizer
储存温度 2-8℃
SMILES string CN(S(=O)(C)=O)C1=NC=CC=C1CNC2=C(C(F)(F)F)C=NC(NC3=CC4=C(C=C3)NC(C4)=O)=N2.O=S(C5=CC=CC=C5)(O)=O

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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