半岛bd体育手机客户端 说明
应用
PF-06869206 has been used to selectively inhibit the activity of sodium-phosphate cotransporter 2a (NaPi2a).
生化/生理作用
PF-06869206 is a selective inhibitor against sodium-phosphate cotransporter 2A (NaPi-2a, NaPi-Iia, Na+/Pi cotransporter 2A, Na+-dependent phosphate cotransporter 2A).
PF-06869206 may be used to treat patients with mineral and hormonal derangements linked with increased cardiovascular risk in chronic kidney disease. This drug might also improve urinary phosphate excretion. PF-06869206 has an ability to decrease phosphate uptake in human embryonic kidney (HEK) cells transfected with mouse or rat renal sodium-dependent phosphate transporter genes (Npt2a).
法律信息
Sold for research purposes under agreement from Pfizer Inc
Pfizer is a registered trademark of Pfizer, Inc.
基本信息
| 经验(实验)分子式 | C15H14ClF3N4O2 |
| 分子量 | 374.75 |
| NACRES | NA.77 |
半岛bd体育手机客户端 性质
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| manufacturer/tradename | Pfizer? |
| 颜色 | white to beige |
| 溶解性 | DMSO: 2 mg/mL, clear |
| 创始人 | Pfizer |
| 储存温度 | room temp |
| SMILES string | ClC1=C(C)NC2=C1N=C(C(F)(F)F)C(C#N)=C2N3C[C@@H](CO)OCC3 |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
