半岛bd体育手机客户端 说明
应用
PB28 dihydrochloride has been used to test its inhibitory effect on potassium voltage-gated channel, shab-related subfamily, member 1, Kv2.1.
生化/生理作用
PB28, a cyclohexylpiperazine derivative, is a sigma 1 (σ1)-Rantagonist. It elicits anti-tumor activity in breast, ovarian and colorectal cancer cell lines.
Selective σ2opioid receptor ligand; putative σ2agonist
基本信息
| 线性分子式 | C24H40Cl2N2O |
| 分子量 | 443.49 |
| MDL编号 | MFCD06798349 |
| PubChem化学物质编号 | 329820345 |
| NACRES | NA.77 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | solid |
| 储存条件 | desiccated |
| 颜色 | white |
| 溶解性 | H2O: ~10 mg/mL at 60 ℃ |
| SMILES string | Cl[H].Cl[H].COc1cccc2C(CCCN3CCN(CC3)C4CCCCC4)CCCc12 |
| InChI | 1S/C24H38N2O.2ClH/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21;;/h6,12,14,20-21H,2-5,7-11,13,15-19H2,1H3;2*1H |
| InChI key | DSRBJOQIBXACIV-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H315 - H319 - H335 |
| 预防措施声明 | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
Sigma-Aldrich
m.cnreagent.com
