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位置: 首页> 品牌> Sigma-Aldrich> ONO-2506

ONO-2506

品牌
Sigma-Aldrich
CAS
185517-21-9
货号
SML2896
规格纯度
≥98% (HPLC)
价格
833.87 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
185517-21-9
ONO-2506
(R)-(-)-2-Propyloctanoic acid
ONO2506
ONO 2506
(2R)-2-Propyloctanoic acid
(-)-(2R)-2-Propyloctanoic acid
(R)-2-Propyloctanoic acid
Arundic acid
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

生化/生理作用

ONO-2506 (arundic acid; (R)-2-propyloctanoic acid) is an inhibitory astrocytes-modulating agent that exerts glioprotective effects against amyloid-β-peptide (Aβ)-induced glial death in astrocyte cultures (50 μM ONO-2506 against 200 μM Aβ25-35, 24 hr; 1321N1 astrocytes) by decreasing both the intracellular and extracellular S100B levels. Blockade of astrocytic activation by ONO-2506in vivois shown to offer therapeutic efficacy in animal models of normal tension glaucoma (10 mg/kg po. mice), spinal cord injury (20 mg/kg/d ip or iv rats), brain seizure, ischemic stroke (10 mg/kg/d ip or iv rats), and Parkinson′s disease (30 mg/kg ip mice).

基本信息

经验(实验)分子式 C11H22O2
分子量 186.29
MDL编号 MFCD08458423

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 oil
颜色 colorless to yellow
储存温度 ?20℃

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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