MoTP

半岛bd体育手机客户端 说明

应用

MoTP may be used in cell signaling and differentiation studies.

包装

5, 25 mg in glass bottle

生化/生理作用

MoTP (also known as 33N14) reversibly blocks the specification of neural crest cells into melanocytes in zebrafish studies. Differentiation of neural crest cell-derived melanoblasts proceeds to late developmental stages, but they fail to reach the terminal stage of melanin production and die. Melanocytotoxicity is dependent on tyrosinase activity which convert it into a toxic form. MoTP specifically ablates only cells that express tyrosinase at high levels, which in the embryo are limited to melanoblasts and newly formed melanocytes. MoTP should be a useful tool for elucidating melanocyte stem cell regeneration, recruitment, and maintenance.

基本信息

经验(实验)分子式	C14H21NO2S
分子量	267.39
MDL编号	MFCD00642470
PubChem化学物质编号	329825117
NACRES	NA.77

半岛bd体育手机客户端 性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to tan
溶解性	DMSO: ≥80 mg/mL
储存温度	?20℃
SMILES string	Oc1ccc(SCCCCN2CCOCC2)cc1
InChI	1S/C14H21NO2S/c16-13-3-5-14(6-4-13)18-12-2-1-7-15-8-10-17-11-9-15/h3-6,16H,1-2,7-12H2
InChI key	YHKNLUTUXZDOQI-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable