半岛bd体育手机客户端 说明
包装
5, 25 mg in glass bottle
生化/生理作用
MLS1547 is a highly efficacious D2 dopamine receptor (D2R) G protein-biased agonist that does not recruit β-arrestin, and is an antagonist of dopamine-stimulated β-arrestin recruitment to the D2 receptor. MLS-1547 is the first D2 receptor agonist with close to full efficacy for G protein signaling (EC50= 370 nM), but no ability to recruit β-arrestin.
基本信息
| 经验(实验)分子式 | C19H19ClN4O |
| 分子量 | 354.83 |
| MDL编号 | MFCD02330713 |
| PubChem化学物质编号 | 329825789 |
| NACRES | NA.77 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to beige |
| 溶解性 | DMSO: 5 mg/mL, clear (warmed) |
| 储存温度 | 2-8℃ |
| SMILES string | OC1=C(CN2CCN(C3=NC=CC=C3)CC2)C=C(Cl)C4=CC=CN=C41 |
| InChI | 1S/C19H19ClN4O/c20-16-12-14(19(25)18-15(16)4-3-7-22-18)13-23-8-10-24(11-9-23)17-5-1-2-6-21-17/h1-7,12,25H,8-11,13H2 |
| InChI key | OPEJNANYABTIGC-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Danger |
| 危险声明 | H301 |
| 预防措施声明 | P301 + P310 + P330 |
| 危险分类 | Acute Tox. 3 Oral |
| 储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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