半岛bd体育手机客户端 说明
包装
5, 25 mg in glass bottle
生化/生理作用
MK-0343 (MRK-409) is a partial agonist for GABAA receptors with comparable Ki values for α1, α2, α3 and α5 containing receptors (0.2 – 0.4 nM). The compound has the greatest agonist activity against α3 receptors, and is brain penatrant, and displays anxiolytic activity in rodent and primate models.
特点和优势
This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
基本信息
| 经验(实验)分子式 | C19H17F2N7O |
| 分子量 | 397.38 |
| MDL编号 | MFCD22683821 |
| PubChem化学物质编号 | 329825556 |
| NACRES | NA.77 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to beige |
| 溶解性 | DMSO: 10 mg/mL, clear |
| 储存温度 | 2-8℃ |
| SMILES string | Cn1ncnc1COc2nn3c(nnc3cc2C4CCC4)-c5c(F)cccc5F |
| InChI | 1S/C19H17F2N7O/c1-27-16(22-10-23-27)9-29-19-12(11-4-2-5-11)8-15-24-25-18(28(15)26-19)17-13(20)6-3-7-14(17)21/h3,6-8,10-11H,2,4-5,9H2,1H3 |
| InChI key | GOIFCXRIFSYPFG-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
