半岛bd体育手机客户端 说明
包装
5, 25 mg in glass bottle
生化/生理作用
Mephetyl tetrazole is a potent and selective Kv1.5 potassium channel blocker. IC50= 330 nM; shows selective atrial prolongation (40%) of effective refractory period (ERP), but no effect on ventricular ERP Kv1.5 channel is a molecular target for the treatment of atrial fibrillation.
特点和优势
This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
基本信息
| 经验(实验)分子式 | C20H22N4O |
| 分子量 | 334.41 |
| MDL编号 | MFCD11045297 |
| PubChem化学物质编号 | 329818044 |
| NACRES | NA.77 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | oil |
| 颜色 | pale yellow |
| 溶解性 | DMSO: >5 mg/mL |
| 储存温度 | 2-8℃ |
| SMILES string | COc1ccc(CCn2nnnc2C3(CC3)c4ccc(C)cc4)cc1 |
| InChI | 1S/C20H22N4O/c1-15-3-7-17(8-4-15)20(12-13-20)19-21-22-23-24(19)14-11-16-5-9-18(25-2)10-6-16/h3-10H,11-14H2,1-2H3 |
| InChI key | VREPWWBWXVLSEF-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
