半岛bd体育手机客户端 说明
一般描述
Glycopyrrolate is a quaternary ammonium compound and it shows structural similarity with atropine.
包装
5, 25 mg in glass bottle
生化/生理作用
Glycopyrrolate is an anti-cholinergic drug. It is a potent controller of drooling, observed in children affected with cerebral palsy. Compared to other muscarinic antagonists, glycopyrrolate has lower CNS (central nervous system) penetration.
Glycopyrrolate is long-acting muscarinic antagonist (LAMA). It is kinetically selective muscarinic M3 receptor antagonist.
特点和优势
This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
基本信息
| 经验(实验)分子式 | C19H28NO3· Br |
| 分子量 | 398.33 |
| EC 号 | 209-887-0 |
| MDL编号 | MFCD00072137 |
| PubChem化学物质编号 | 329825100 |
| NACRES | NA.77 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 储存条件 | desiccated |
| 颜色 | white to tan |
| 溶解性 | H2O: ≥24 mg/mL |
| 创始人 | Novartis |
| 储存温度 | 2-8℃ |
| SMILES string | [Br-].C[N+]1(C)CCC(C1)OC(=O)C(O)(C2CCCC2)c3ccccc3 |
| InChI | 1S/C19H28NO3.BrH/c1-20(2)13-12-17(14-20)23-18(21)19(22,16-10-6-7-11-16)15-8-4-3-5-9-15;/h3-5,8-9,16-17,22H,6-7,10-14H2,1-2H3;1H/q+1;/p-1 |
| InChI key | VPNYRYCIDCJBOM-UHFFFAOYSA-M |
| Gene Information | human ... CHRM1(1128), CHRM3(1131) |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H302 - H315 - H319 - H335 |
| 预防措施声明 | P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338 |
| 危险分类 | Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
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