半岛bd体育手机客户端 说明
包装
5, 25 mg in glass bottle
生化/生理作用
CYP3cide is a mechanism-based inhibitor of cytochrome P4503A4 that can be used to distinguish the contributions of CYP3A4 versus CYP3A5 on drug metabolism. The IC50values for inhibition of Midazolam 1′-Hydroxylase activity of recombinant CYP3A4 and CYP3A5 by CYP3cide are 0.3 and 17 mM, respectively.
特点和优势
This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
其他说明
This compound was developed by Pfizer for ADME/Tox research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.
To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
法律信息
Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
基本信息
| 经验(实验)分子式 | C26H32N8 |
| 分子量 | 456.59 |
| MDL编号 | MFCD22417344 |
| PubChem化学物质编号 | 329823769 |
| NACRES | NA.77 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| manufacturer/tradename | Pfizer? |
| 颜色 | white to beige |
| 溶解性 | DMSO: >10 mg/mL (warmed) |
| 创始人 | Pfizer |
| 储存温度 | room temp |
| SMILES string | Cc1ccc(cc1)-c2c(cnn2C)-c3nn(C)c4ncnc(N5CC[C@@H](C5)N6CCCCC6)c34 |
| InChI | 1S/C26H32N8/c1-18-7-9-19(10-8-18)24-21(15-29-31(24)2)23-22-25(32(3)30-23)27-17-28-26(22)34-14-11-20(16-34)33-12-5-4-6-13-33/h7-10,15,17,20H,4-6,11-14,16H2,1-3H3/t20-/m0/s1 |
| InChI key | WDWIMDKOXZZYHH-FQEVSTJZSA-N |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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