CGP52432

半岛bd体育手机客户端 说明

应用

CGP52432 has been used as a γ-aminobutyric acid B (GABA_B) antagonist:

• to study its effects on the simulation of the onset of status epilepticus (SE) in mice
• for voltage-clamp recording in mice neurons
• to study its effects on the GABA_Breceptor-mediated neurotransmission in guinea pig hippocampus

包装

5, 25 mg in glass bottle

生化/生理作用

CGP52432 participates in inhibiting the glycine overflow in the hippocampus.
CGP52432 is a very potent antagonist of GABA_Breceptors. (IC₅₀= 85 nM).

特点和优势

This compound is featured on the GABAB Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

其他说明

注意：不要冻存。

基本信息

经验(实验)分子式	C15H24Cl2NO4P
分子量	384.24
NACRES	NA.77

半岛bd体育手机客户端 性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
储存条件	desiccated
颜色	white to beige
溶解性	H2O: 1 mg/mL, clear (warmed)
储存温度	2-8℃
InChI	1S/C15H24Cl2NO4P/c1-3-21-15(22-4-2)23(19,20)9-5-8-18-11-12-6-7-13(16)14(17)10-12/h6-7,10,15,18H,3-5,8-9,11H2,1-2H3,(H,19,20)
InChI key	GJZVQXWEIYRHBE-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable