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CASIN

品牌
Sigma-Aldrich
CAS
425399-05-9
货号
SML1253
规格纯度
≥98% (HPLC)
价格
1396.09 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
425399-05-9
CASIN
2-[(2,3,4,9-Tetrahydro-6-phenyl-1H-carbazol-1-yl)amino]ethanol
Cdc42 Activity-Specific Inhibitor
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

CASIN has been used as a cell division control protein 42 homolog (Cdc42) inhibitor:

  • to study its effects on the stimulation of extracellular vesicles (EVs) in intestinal epithelial cells
  • to study its effects on mice jejunum
  • to study its effects on microbial adhesion-triggered endocytosis (MATE) vesicle morphology in segmented filamentous bacteria (SFB)-colonized mice

包装

5, 25 mg in glass bottle

生化/生理作用

CASIN is an inhibitor of Cdc42 GTPase, a small GTPase of the Rho-subfamily that plays important roles in cytoskeleton organization, cell cycle progression, signal transduction, and vesicle trafficking. CASIN generated a rejuvenated phenotype of Hematopoietic stem cells (HSCs), reversing the aging-related and polarity phenotype of aged HSCs to that of young HSCsin vivo..

基本信息

经验(实验)分子式 C20H22N2O
分子量 306.40
MDL编号 MFCD01853271
PubChem化学物质编号 329825745

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 powder
颜色 , white to very dark brown
溶解性 DMSO: 20 mg/mL, clear
储存温度 2-8℃
SMILES string OCCNC1CCCC2=C1NC3=C2C=C(C4=CC=CC=C4)C=C3
InChI 1S/C20H22N2O/c23-12-11-21-19-8-4-7-16-17-13-15(14-5-2-1-3-6-14)9-10-18(17)22-20(16)19/h1-3,5-6,9-10,13,19,21-23H,4,7-8,11-12H2
InChI key RXIUMAOXORBRCY-UHFFFAOYSA-N

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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