BAY 41-2272

半岛bd体育手机客户端 说明

应用

BAY 41-2272 has been used for the stimulation of guanylate cyclase in heart and neurons.

包装

5, 25 mg in glass bottle

生化/生理作用

BAY 41-2272 is an activator of soluble guanylate cyclase at a novel, NO-independent regulatory site. BAY 41-2272 is the first product that stimulates sGC through a non-NO mechanism. BAY 41-2272 inhibits platelet aggregation and induces vasorelaxation without nitrate tolerance.

特点和优势

This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

基本信息

经验(实验)分子式	C20H17FN6
分子量	360.39
MDL编号	MFCD06411391
PubChem化学物质编号	24892096
NACRES	NA.77

半岛bd体育手机客户端 性质

质量水平	100
测定	≥97% (HPLC)
形式	powder
颜色	white to light brown
mp	210.5-211.4 ℃
溶解性	DMSO: 5 mg/mL, clear (warmed)
创始人	Bayer
储存温度	2-8℃
SMILES string	Nc1nc(ncc1C2CC2)-c3nn(Cc4ccccc4F)c5ncccc35
InChI	1S/C20H17FN6/c21-16-6-2-1-4-13(16)11-27-20-14(5-3-9-23-20)17(26-27)19-24-10-15(12-7-8-12)18(22)25-19/h1-6,9-10,12H,7-8,11H2,(H2,22,24,25)
InChI key	ATOAHNRJAXSBOR-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves