APC366 trifluoroacetate

品牌

Sigma-Aldrich

CAS

158921-85-8

货号

SML2490

包装型号

规格纯度

≥97% (HPLC)

价格

1023.54 元 *本价格含增值税费

促销

数量

- +

半岛bd体育手机客户端名称：

158921-85-8
APC366 trifluoroacetate
APC 366 trifluoroacetate
N2-[(1-Hydroxy-2-naphthalenyl)carbonyl]-L-arginyl-L-prolinamide trifluoroacetate
N-(1-Hydroxy-2-naphthoyl)-L-arginyl-L-prolinamide

半岛bd体育手机客户端介绍：

半岛bd体育手机客户端说明

生化/生理作用

APC366 is a selective inhibitor of mast cell tryptase, which is involved with allergenic response. It thereby also inhibits protease-activated receptor PAR2, a G-protein-coupled receptor that is activated by mast cell tryptase. Tryptase has been proposed to be involved in fibrosis, joint inflammation and also in promoting breast cancer angiogenesis, all of which APC366 inhibited.

基本信息

经验(实验)分子式	C₂₂H₂₈N₆O₄· xC₂HF₃O₂
分子量	440.50 (free base basis)

半岛bd体育手机客户端性质

测定	≥97% (HPLC)
形式	lyophilized powder
颜色	white to off-white
运输	wet ice
储存温度	?20℃
SMILES string	FC(F)(C(O)=O)F.NC(NCCC[C@@H](C(N1CCC[C@H]1C(N)=O)=O)NC(C2=C(O)C3=CC=CC=C3C=C2)=O)=N