半岛bd体育手机客户端 说明
包装
5, 25 mg in glass bottle
生化/生理作用
ADX71743 is known to negatively regulate the effect of mGlu7 (metabotropic glutamate receptor subtype 7), which is associated with a number of anxiety disorders.
ADX71743 is a brain-penetrant, selective and potent negative allosteric modulator of metabotropic glutamate receptor 7 (mGlu7). In one study ADX71743 exhibited an anxiolytic-like profile in rat and mouse models without causing impairment of locomotor activity. In another study it induced absence epileptic seizures and lethargy.
基本信息
| 经验(实验)分子式 | C17H19NO2 |
| 分子量 | 269.34 |
| MDL编号 | MFCD30474715 |
| NACRES | NA.77 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to beige |
| 溶解性 | DMSO: 5 mg/mL, clear (warmed) |
| 储存温度 | ?20℃ |
| SMILES string | CC1=CC(C)=CC=C1C2CC(OC(CC)=N3)=C3C(C2)=O |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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