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Acetylethylcholine mustard hydrochloride

品牌
Sigma-Aldrich
CAS
103994-00-9
货号
C001
规格纯度
>97% (GC), powder
价格
926.4 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
103994-00-9
Acetylethylcholine mustard hydrochloride
Acetyl AF-64
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

Acetylethylcholine mustard hydrochloride has been used as a precursor in ethylcholine aziridinium (AF64A) preparation. It has also been used in the pharmacokinetic study to investigate its role in neuromuscular junction (NMJ) signal transmission and function.

包装

5, 25 mg in glass bottle

生化/生理作用

Acetylethylcholine mustard is a precursor for ethylcholine mustard aziridinium ion (AF-64A); irreversible ligand for the high affinity choline transport system; specific presynaptic long action cholinotoxin; inhibitor of choline acetyl-transferase.
Acetylethylcholine mustard hydrochloride can reduce the contraction frequency of the myotubes by inhibiting the synthesis of acetylethylcholine (Ach) with the half-maximal inhibitory concentration (IC50) of 1.22 mM.

注意

Extremely hygroscopic.

基本信息

经验(实验)分子式 C8H16ClNO2· HCl
分子量 230.13
MDL编号 MFCD00055153
PubChem化学物质编号 329774756
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 100
测定 >97% (GC)
形式 powder
储存条件 desiccated
颜色 white
mp 78-81 ℃
溶解性 H2O: >5 mg/mL
ethanol: soluble
methanol: soluble
储存温度 ?20℃
SMILES string Cl[H].CCN(CCCl)CCOC(C)=O
InChI 1S/C8H16ClNO2.ClH/c1-3-10(5-4-9)6-7-12-8(2)11;/h3-7H2,1-2H3;1H
InChI key CHWPASAPXMNLKO-UHFFFAOYSA-N

安全信息

象形图 GHS06GHS08
警示用语: Danger
危险声明 H300 + H310 + H330 - H315 - H319 - H335 - H370
预防措施声明 P260 - P262 - P280 - P302 + P352 + P310 - P304 + P340 + P310 - P305 + P351 + P338
危险分类 Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 1 - STOT SE 3
靶器官 Nervous system, Respiratory system
储存分类代码 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK WGK 3
闪点(F) 204.8 °F - closed cup
闪点(C) 96 ℃ - closed cup

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