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位置: 首页> 品牌> Sigma-Aldrich> VU0071063

VU0071063

品牌
Sigma-Aldrich
CAS
333415-38-6
货号
SML1142
规格纯度
≥98% (HPLC)
价格
1117.23 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
333415-38-6
VU0071063
7-[[4-(1,1-Dimethylethyl)phenyl]methyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

包装

5, 25 mg in glass bottle

生化/生理作用

VU0071063 is also known as [7-(4-(tert-butyl)benzyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione]. It serves as a major compound for examining β-cell physiology, KATPchannel gating and a new chemical scaffold for evolving enhanced activators with medicinal chemistry.
VU0071063 is a potent activator of Kir6.2/SUR1 KATP channels (EC50= 10.3 μM). VU0071063 reversibly inhibits glucose-stimulated calcium influx in mouse β-islet cells. The compound VU0071063 has no affect on Kir6.2/SUR2A channels.

基本信息

经验(实验)分子式 C18H22N4O2
分子量 326.39
MDL编号 MFCD02648040
PubChem化学物质编号 329825676

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 powder
颜色 white to beige
溶解性 DMSO: 10 mg/mL, clear
储存温度 2-8℃
SMILES string CN(C1=C2N(CC3=CC=C(C(C)(C)C)C=C3)C=N1)C(N(C)C2=O)=O
InChI 1S/C18H22N4O2/c1-18(2,3)13-8-6-12(7-9-13)10-22-11-19-15-14(22)16(23)21(5)17(24)20(15)4/h6-9,11H,10H2,1-5H3
InChI key ZFZAIHKQJBMYLO-UHFFFAOYSA-N

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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