半岛bd体育手机客户端 说明
应用
UCL 1684 ditrifluoroacetate hydrate has been used for analyzing the mechanism for ammonium-mediated displacement of the protonated analyte from analyte-trifluoroacetic acid (TFA) ion-pair. UCL 1684 has also been used as a potassium channel inhibitor to study CNP (C-type natriuretic peptide)-induced relaxations in pig coronary arteries.
包装
5, 25 mg in glass bottle
生化/生理作用
UCL 1684 is a potent non-peptide blocker of the apamin-sensitive Ca2+-activated K+channel. It comprises two quinolinium rings and is similar to apamin arginine residue. UCL 1684 inhibits calcium-activated K current (Kslow) and modulates islet β-cell.
特点和优势
This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
制备说明
UCL 1684 ditrifluoroacetate hydrate is soluble in water at 10 mg/ml.
基本信息
线性分子式 | (C34H30N4)2+· (C2F3O2-)2· xH2O |
分子量 | 720.66 (anhydrous basis) |
PubChem化学物质编号 | 24900684 |
NACRES | NA.77 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
颜色 | white to off-white |
溶解性 | DMSO: 10 mg/mL |
SMILES string | [H]O[H].FC(F)(C(O)=O)F.FC(F)(C(O)=O)F.C12=CC=CC=C1C(NCC3=CC=C(CNC4=CC=[N+](C5)C6=C4C=CC=C6)C=C3)=CC=[N+]2CC7=CC=CC5=C7 |
InChI | 1S/C34H28N4.2C3H3F3O2.H2O/c1-3-10-33-29(8-1)31-16-18-37(33)23-27-6-5-7-28(20-27)24-38-19-17-32(30-9-2-4-11-34(30)38)36-22-26-14-12-25(13-15-26)21-35-31;2*4-3(5,6)1-2(7)8;/h1-20H,21-24H2;2*1H2,(H,7,8);1H2/b35-31+,36-32+;;; |
InChI key | YROHEYZVNZITJN-DDVHGCDCSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich