SYUIQ-5

半岛bd体育手机客户端 说明

应用

SYUIQ-5 may be used in autophagy and DNA damage-inducing cell signaling studies.

包装

5, 25 mg in glass bottle

生化/生理作用

SYUIQ-5 is a Cryptolepine derivative, which induces and stabilizes G-quadruplexes. In CNE2 and HeLa cancer cells SYUIQ-5 triggers rapid and potent telomere DNA damage through TRF2 delocalization from telomeres and induces cell death by autophagy. In low concentration the compound caused senescence and telomere shortening. It is a potent cytotoxic agent.

基本信息

经验(实验)分子式	C20H22N4
分子量	318.42
MDL编号	MFCD17215940
PubChem化学物质编号	329824555
NACRES	NA.77

半岛bd体育手机客户端 性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	yellow
溶解性	DMSO: ≥20 mg/mL
储存温度	2-8℃
SMILES string	CN(C)CCCNc1c2ccccc2nc3c4ccccc4[nH]c13
InChI	1S/C20H22N4/c1-24(2)13-7-12-21-18-14-8-3-5-10-16(14)22-19-15-9-4-6-11-17(15)23-20(18)19/h3-6,8-11,23H,7,12-13H2,1-2H3,(H,21,22)
InChI key	CTDCVGDSVHUYMA-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H400
预防措施声明	P273
危险分类	Aquatic Acute 1
储存分类代码	13 - Non Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable