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SW02

品牌
Sigma-Aldrich
CAS
1010820-68-4
货号
S5951
包装型号
规格纯度
价格
1596.03 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
半岛bd体育手机客户端 名称:
1010820-68-4
SW02
4-(4-Bromophenyl)-5-(ethoxycarbonyl)-3,4-dihydro-6-methyl-2-oxo-1(2H)-pyrimidinebutanoic acid methyl ester
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

SW02 may be used in Hsp70-mediated cell signaling studies.

包装

5, 25 mg in glass bottle

生化/生理作用

SW02 is a specific activator/agonist of Hsp70. Hsp70 is of particular interest in diseases caused by protein misfolding, such as tau and Aβ in Alzheimer′s. SW02 increases Hsp70 ATPase activity, resulting in increased tau protein but not other disease-related proteins in cells. Hsp70 prevents aggregation of Aβ peptide, as shown by treatment with SW02.

基本信息

经验(实验)分子式C19H23BrN2O5
分子量439.30
MDL编号MFCD17215960
PubChem化学物质编号329824558
NACRESNA.77

半岛bd体育手机客户端 性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to off-white
溶解性DMSO: ≥20 mg/mL
储存温度2-8℃
SMILES stringCCOC(=O)C1=C(C)N(CCCC(=O)OC)C(=O)NC1c2ccc(Br)cc2
InChI1S/C19H23BrN2O5/c1-4-27-18(24)16-12(2)22(11-5-6-15(23)26-3)19(25)21-17(16)13-7-9-14(20)10-8-13/h7-10,17H,4-6,11H2,1-3H3,(H,21,25)
InChI keyYFZRMRYVWWUQME-UHFFFAOYSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H301
预防措施声明P301 + P310
危险分类Acute Tox. 3 Oral
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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