半岛bd体育手机客户端 说明
生化/生理作用
SK609 (ES609) is a Dopamine D3 receptor (D3R) selective agonist with a bias towards the G-protein-dependent pathway rather than recruiting β-arrestin-2 and an EC50 value of 113.9 nM for activation of ERK1/2 phosphorylation. SK609 has been shown to reverse akinesia and reduce L-dopa-induced dyskinesia in a hemiparkinsonian rat model of Parkinson′s desease. It does not induce desensitization of D3R.
基本信息
经验(实验)分子式 | C10H14ClN · HCl |
分子量 | 220.14 |
半岛bd体育手机客户端 性质
测定 | ≥98% (HPLC) |
形式 | powder |
储存条件 | protect from light under inert gas |
颜色 | white to beige |
溶解性 | H2O: 2 mg/mL, clear |
储存温度 | 2-8℃ |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich