半岛bd体育手机客户端 说明
生化/生理作用
SGC-SMARCA-BRDVIII is a potent, SMARCA2/4 and PB1(bromo 5)-selective SWI/SNF bromodomain (BRD) inhibitor that effectively blocks adipocyte differentiation in 3T3-L1 murine fibroblast cultures (1 μM) by preventing the expression of key adipogenesis genes, including PPARγ, C/EBPα, and FABP4, with a >10-fold higher potency than PFI-3.
基本信息
| 经验(实验)分子式 | C19H25N5O3 |
| 分子量 | 371.43 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to beige |
| 溶解性 | DMSO: 2 mg/mL, clear |
| 储存温度 | 2-8℃ |
| SMILES string | O=C(N1CCN(CC1)C2=C(N)N=NC(C3=CC=CC=C3O)=C2)OC(C)(C)C |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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