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SC-236

品牌
Sigma-Aldrich
CAS
170569-86-5
货号
PZ0106
规格纯度
≥98% (HPLC)
价格
1191.25 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
170569-86-5
SC-236
4-[5-(4-Chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide
SC-58236
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

SC-236 has been used as a COX-2 inhibitor to study its effects on the mechano-reflex in rats.

包装

5, 25 mg in glass bottle

生化/生理作用

SC-236 exhibits anti-tumor activity in gastric cancer cells by modulating activator protein-1 (AP-1) expression and by blocking the anchorage-independent cell growth. It also exhibits a protective effect against cartilage damage by minimizing the inflammation and pain in osteoarthritis. It is also reported to treat allergic inflammation.
SC-236 is a cyclooxygenase-2 (COX-2) inhibitor.

其他说明

This compound was developed by Pfizer for Lipid Signaling research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.

基本信息

经验(实验)分子式 C16H11ClF3N3O2S
分子量 401.79
MDL编号 MFCD00941297
PubChem化学物质编号 329823698
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 powder
manufacturer/tradename Pfizer?
颜色 white to off-white
溶解性 DMSO: >20 mg/mL
创始人 Pfizer
储存温度 2-8℃
SMILES string NS(=O)(=O)c1ccc(cc1)-n2nc(cc2-c3ccc(Cl)cc3)C(F)(F)F
InChI 1S/C16H11ClF3N3O2S/c17-11-3-1-10(2-4-11)14-9-15(16(18,19)20)22-23(14)12-5-7-13(8-6-12)26(21,24)25/h1-9H,(H2,21,24,25)
InChI key NSQNZEUFHPTJME-UHFFFAOYSA-N

安全信息

象形图 GHS06
警示用语: Danger
危险声明 H301
预防措施声明 P301 + P310
危险分类 Acute Tox. 3 Oral
储存分类代码 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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