半岛bd体育手机客户端 说明
应用
SB-204070 hydrochloride was used to study the role of 5-HT metabolites in trypsin-induced anion secretion in mouse cecum.
包装
5, 25 mg in glass bottle
生化/生理作用
SB-204070 is a highly potent and specific antagonist of 4-HT4receptor. It inhibits cholinergic and noncholinergic transmission and blocks the contractions of proximal colon in guinea pigs and relaxation of human colon circular smooth muscle.
Selective 5-HT4serotonin receptor antagonist.
法律信息
Manufactured and sold under exclusive license from GlaxoSmithKline Pharmaceuticals
基本信息
| 经验(实验)分子式 | C19H27ClN2O4· HCl |
| 分子量 | 419.34 |
| MDL编号 | MFCD03453014 |
| PubChem化学物质编号 | 24278704 |
| NACRES | NA.77 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥97% (HPLC) |
| 形式 | solid |
| mp | 243-245 ℃ (lit.) |
| 溶解性 | H2O: 20 mg/mL (with heating) |
| SMILES string | Cl[H].CCCCN1CCC(CC1)COC(=O)c2cc(Cl)c(N)c3OCCOc23 |
| InChI | 1S/C19H27ClN2O4.ClH/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18;/h11,13H,2-10,12,21H2,1H3;1H |
| InChI key | YEQGKAOSYSXEPU-UHFFFAOYSA-N |
| Gene Information | human ... HTR4(3360) |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
