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位置: 首页> 品牌> Sigma-Aldrich> SB 657510

SB 657510

品牌
Sigma-Aldrich
CAS
474960-44-6
货号
S7326
规格纯度
≥98% (HPLC)
价格
1491.95 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
474960-44-6
SB 657510
SB-657510
2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxy-benzenesulfonamide
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

SB 657510 may be used to study the urotensin II receptor-mediated signaling.

包装

5, 25 mg in glass bottle

生化/生理作用

SB 657510 slows development of diabetes-associated atherosclerosis in mouse model of diabetes.1
SB-657510 is a selective urotensin-II (UT) receptor antagonist. Human urotensin-II (hU-II) is proposed to play a significant role in cardiorenal and metabolic disease states, including heart failure, atherosclerosis, hypertension.

特点和优势

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

基本信息

经验(实验)分子式 C19H22BrClN2O5S
分子量 505.81
PubChem化学物质编号 329824581
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 powder
颜色 white to off-white
溶解性 DMSO: ≥30 mg/mL
创始人 GlaxoSmithKline
储存温度 room temp
SMILES string COc1cc(Br)c(cc1OC)S(=O)(=O)Nc2ccc(Cl)c(O[C@@H]3CCN(C)C3)c2
InChI 1S/C19H22BrClN2O5S/c1-23-7-6-13(11-23)28-16-8-12(4-5-15(16)21)22-29(24,25)19-10-18(27-3)17(26-2)9-14(19)20/h4-5,8-10,13,22H,6-7,11H2,1-3H3/t13-/m1/s1
InChI key KQCZCINJGIRLCD-CYBMUJFWSA-N

安全信息

象形图 GHS07
警示用语: Warning
危险声明 H315 - H319 - H335
预防措施声明 P261 - P305 + P351 + P338
危险分类 Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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