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位置: 首页> 品牌> Sigma-Aldrich> 2′-Hydroxy-2,4,4′,5,6′-pentamethoxychalcone

Rubone

2′-Hydroxy-2,4,4′,5,6′-pentamethoxychalcone

品牌
Sigma-Aldrich
CAS
73694-15-2
货号
SML1311
包装型号
规格纯度
≥98% (HPLC)
价格
692.77 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
73694-15-2
Rubone
2′-Hydroxy-2,4,4′,5,6′-pentamethoxychalcone
(2E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(2,4,5-trimethoxyphenyl)-2-propen-1-one
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

包装

5, 25 mg in glass bottle

生化/生理作用

Rubone has strong anticancer activity. Rubone and paclitaxel (PTX) combination therapy retarded cancer cell growth, migration and cancer stem-like cells (CSC) population growth.
Rubone is a miR34a modulator that specifically restores miR34a in hepatocellular carcinoma cells with wild-type or mutated p53. Rubone potently inhibits growth of hepatocellular carcinoma in a mouse xenograft model. Rubone does not effect the growth of nontumorigenic human hepatocytes.
Rubone is a miR34a modulator that specifically restores miR34a in hepatocellular carcinoma cells.

基本信息

经验(实验)分子式 C20H22O7
分子量 374.38
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 powder
储存条件 desiccated
颜色 yellow to orange
溶解性 DMSO: 2 mg/mL, clear (warmed)
储存温度 2-8℃

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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