半岛bd体育手机客户端 说明
生化/生理作用
Pt-ttpy, a metallo-organic complex, is a G-quadruplex ligand that potently induces significant telomere-associated DNA damage in cancer cells. It inhibits telomerase and/or telomere functions. Pt-ttpy induces number of chromatin defects in mitosis including chromatin bridges, ultrafine bridges (UFBs), and double-stranded breaks (DSBs).
基本信息
| 经验(实验)分子式 | C22H17Cl2N3Pt |
| 分子量 | 589.37 |
半岛bd体育手机客户端 性质
| 测定 | >97% (NMR) |
| 形式 | powder |
| 颜色 | faint yellow to dark orange |
| 溶解性 | DMSO: 0.2 mg/mL (warmed) |
| 储存温度 | 2-8℃ |
| SMILES string | CC1=CC=C(C2=CC(C3=[N+]4C=CC=C3)=[N+]5C(C6=CC=CC=[N+]6[Pt-2]54Cl)=C2)C=C1.[Cl-] |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
