半岛bd体育手机客户端 说明
包装
5, 25 mg in glass bottle
生化/生理作用
PQ-10 is a potent and selective inhibitor of phosphodiesterase 10A (PDE10). Apparently, PQ-10 enhances basic auditory information processing in rats. PQ-10 as other PED10 inhibitors suppresses a growth of human non-small cell lung cancer (NSCLC) cell lines.
PQ-10 (6,7-dimethoxy-4-[3-(quinoxalin-2-yloxy)pyrrolidin-1-yl]quinazoline), is capable of suppressing tumor cell growth. It can also reverse the RO-4-1284-induced sedation and catalepsy.
特点和优势
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基本信息
经验(实验)分子式 | C22H21N5O3 |
分子量 | 403.43 |
MDL编号 | MFCD12828216 |
PubChem化学物质编号 | 329825657 |
NACRES | NA.77 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | white to beige |
溶解性 | DMSO: 10 mg/mL, clear |
储存温度 | 2-8℃ |
SMILES string | COC1=CC2=C(N3C[C@H](OC4=CN=C(C=CC=C5)C5=N4)CC3)N=CN=C2C=C1OC |
InChI | 1S/C22H21N5O3/c1-28-19-9-15-18(10-20(19)29-2)24-13-25-22(15)27-8-7-14(12-27)30-21-11-23-16-5-3-4-6-17(16)26-21/h3-6,9-11,13-14H,7-8,12H2,1-2H3/t14-/m1/s1 |
InChI key | UBIIFKJMNRPNMT-CQSZACIVSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich