P7C3

半岛bd体育手机客户端 说明

应用

P7C3 is an aminopropyl carbazole agent with proneurogenic and neuroprotective properties in newborn neural precursor cells of the dentate gyrus. Its analogs may be used in neurodegenerative disease research to study the process of neurogenesis in brain regions such as the subgranular zone of the hippocampal dentate gyrus. P7C3 and its analogs may be used to study its pharmacokinetics, metabolism, safety, efficacy and methods of delivery as potential drug for the treatment of condition such as Alzheimer′s disease, Parkinson′s disease, amyotrophic lateral sclerosis and traumatic brain injury.

包装

5, 25 mg in glass bottle

生化/生理作用

P7C3 is neurogenic and protects new neurons against apoptosis. These activities may be related to its capacity to protect mitochondrial integrity.

Degeneration of the hippocampus is an early manifestation of Alzheimer′s disease. P7C3 promotes neurogenesis in the subgranular zone of the hippocampal dentate gyrus, the site of normal neurogenesis in adult mammals, making it an important lead compound in development of new Alzheimer′s treatments.

基本信息

经验(实验)分子式	C21H18Br2N2O
分子量	474.19
MDL编号	MFCD00572918
PubChem化学物质编号	329798864

半岛bd体育手机客户端 性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to off-white
溶解性	DMSO: 34 mg/mL
储存温度	2-8℃
SMILES string	OC(CNc1ccccc1)Cn2c3ccc(Br)cc3c4cc(Br)ccc24
InChI	1S/C21H18Br2N2O/c22-14-6-8-20-18(10-14)19-11-15(23)7-9-21(19)25(20)13-17(26)12-24-16-4-2-1-3-5-16/h1-11,17,24,26H,12-13H2
InChI key	FZHHRERIIVOATI-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Danger
危险声明	H301 - H318
预防措施声明	P280 - P301 + P310 + P330 - P305 + P351 + P338 + P310
危险分类	Acute Tox. 3 Oral - Eye Dam. 1
储存分类代码	6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable