半岛bd体育手机客户端 说明
包装
5, 25 mg in glass bottle
生化/生理作用
NSC59984 targets various mutant p53 to restore wild-type p53 pathway via the activation of p73 in cancer cells. NSC59984 depletes a gain of function (GOF p53 mutants. NSC59984 is not cytotoxic against normal cells.
基本信息
经验(实验)分子式 | C12H15N3O4 |
分子量 | 265.27 |
MDL编号 | MFCD29905462 |
PubChem化学物质编号 | 329825487 |
NACRES | NA.77 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | yellow to brown |
溶解性 | DMSO: 5 mg/mL, clear (warmed) |
储存温度 | 2-8℃ |
SMILES string | CN1CCN(C(/C=C/C2=CC=C([N+]([O-])=O)O2)=O)CC1 |
InChI | 1S/C12H15N3O4/c1-13-6-8-14(9-7-13)11(16)4-2-10-3-5-12(19-10)15(17)18/h2-5H,6-9H2,1H3/b4-2+ |
InChI key | QKTRIGNWBRHBFV-DUXPYHPUSA-N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H315 - H319 - H335 |
预防措施声明 | P302 + P352 - P305 + P351 + P338 |
危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
靶器官 | Respiratory system |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich