Nifetepimine - 半岛电竞官方网址

半岛bd体育手机客户端名称：

110448-29-8
Nifetepimine
1,2,3,4-Tetrahydro-6-methyl-4-(3-nitrophenyl)-2-oxo-5-pyrimidinecarboxylic acid ethyl ester
5-Ethoxycarbonyl-6-methyl-4-(3-nitrophenyl)-3,4-dihydropyrimidin-2(1H)-one
6-Methyl-4-(3-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid ethyl ester
Ethyl-4-(3-nitrophenyl)-6-methyl-2-oxo-1,2,3,4 tetrahydropyrimidine-5 carboxylate

半岛bd体育手机客户端介绍：

半岛bd体育手机客户端说明

包装

5, 25 mg in glass bottle

生化/生理作用

Nifetepimine is a dihydropyrimidone calcium channel blocker that down-modulates SERCA3 (sarco/endoplasmic reticulum Ca²⁺ -ATPase 3) pump, and protects of the CD4⁺ T cells from tumor-induced apoptosis. Nifetepimine induces apoptotic cell death in triple negative breast cancer (TNBC) cells by stimulation of cross-talk between ER stress and the MEK/ERK pathway.

基本信息

经验(实验)分子式	C₁₄H₁₅N₃O₅
分子量	305.29
MDL编号	MFCD00128568
PubChem化学物质编号	329825824
NACRES	NA.77

半岛bd体育手机客户端性质

质量水平	100
测定	≥95% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 10 mg/mL, clear
储存温度	2-8℃
SMILES string	O=C(OCC)C1=C(C)NC(NC1C2=CC([N+]([O-])=O)=CC=C2)=O
InChI	1S/C14H15N3O5/c1-3-22-13(18)11-8(2)15-14(19)16-12(11)9-5-4-6-10(7-9)17(20)21/h4-7,12H,3H2,1-2H3,(H2,15,16,19)
InChI key	PPBNQKLDXXHPMH-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302 - H319
预防措施声明	P280 - P301 + P312 + P330 - P305 + P351 + P338 - P337 + P313
危险分类	Acute Tox. 4 Oral - Eye Irrit. 2
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable