半岛bd体育手机客户端 说明
包装
5, 25 mg in glass bottle
生化/生理作用
NCX 4040 is a nitric oxide-donating form of aspirin. NCX 4040 inhibits cyclooxygenase activity and releases NO, which can down-regulate COX2 expression and reduce the levels of superoxide accumulation. In the human monocytic cell line THP1, the compound inhibits PGE2 production and cytokine expression, and appears to stabilize IkB by inhibiting proteasome function. NCX 4040 has been shown to induce apoptosis in several tumor cell lines.
特点和优势
This compound is featured on the Nitric Oxide Synthases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
基本信息
| 经验(实验)分子式 | C16H13NO7 |
| 分子量 | 331.28 |
| MDL编号 | MFCD08062164 |
| PubChem化学物质编号 | 329825409 |
| NACRES | NA.77 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 储存条件 | protect from light |
| 颜色 | white to beige |
| 溶解性 | DMSO: 15 mg/mL (clear solution) |
| 储存温度 | ?20℃ |
| SMILES string | CC(=O)Oc1ccccc1C(=O)Oc2ccc(CO[N+]([O-])=O)cc2 |
| InChI | 1S/C16H13NO7/c1-11(18)23-15-5-3-2-4-14(15)16(19)24-13-8-6-12(7-9-13)10-22-17(20)21/h2-9H,10H2,1H3 |
| InChI key | CTHNKWFUDCMLIQ-UHFFFAOYSA-N |
安全信息
| 象形图 |    |
| 警示用语： | Danger |
| 危险声明 | H317 - H318 - H400 |
| 预防措施声明 | P273 - P280 - P302 + P352 - P305 + P351 + P338 + P310 |
| 危险分类 | Aquatic Acute 1 - Eye Dam. 1 - Skin Sens. 1 |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
