ME0328

半岛bd体育手机客户端 说明

包装

5, 25 mg in glass bottle

生化/生理作用

ME0328 is a selective inhibitor of ADP-ribosyltransferase-3/poly(ADP-ribose) polymerase-3 (ARTD3/PARP3), a PARP family member involved in DNA repair. ME0328 is the most potent isomer of the four ARTD3 ADP-ribosyltransferase inhibitors. ME0328 selectively inhibits ARTD3 (IC₅₀of 890 nM) with weaker activity against ARTD1 and ARTD2 (IC₅₀6.3 and 10.8 μM, respectively), and no significant activity (IC₅₀>30 μM) against any other ARTD enzyme. ME0328 appears to be the first selective inhibitor of ARTD3/PARP3.

特点和优势

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基本信息

经验(实验)分子式	C19H19N3O2
分子量	321.37
NACRES	NA.77

半岛bd体育手机客户端 性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 10 mg/mL, clear
储存温度	room temp

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable