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位置: 首页> 品牌> Sigma-Aldrich> LY 320135

LY 320135

品牌
Sigma-Aldrich
CAS
176977-56-3
货号
L5295
包装型号
规格纯度
≥98% (HPLC)
价格
1151.92 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
176977-56-3
LY 320135
4-[6-Methoxy-2-(4-methoxyphenyl)benzofuran-3-carbonyl]benzonitrile
[6-Methoxy-2-(4-methoxyphenyl)benzo[b]furan-3-yl](4-cyanophenyl)methanone
LY320135
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

包装

5, 25 mg in glass bottle

生化/生理作用

LY320135 is a potent CB1 receptor antagonist/inverse agonist (Ki = 141 nM) with greater than 70-fold selectivity over CB2 receptors (Ki > 10 μM). Structurally dissimilar from SR 141716A and AM 251. Shows weak binding to both 5-HT2 (Ki = 6.4 μM) and muscarinic receptors (Ki = 2.1 μM)

特点和优势

This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

基本信息

经验(实验)分子式 C24H17NO4
分子量 383.40
MDL编号 MFCD00945878
PubChem化学物质编号 329817622
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 powder
颜色 orange
溶解性 DMSO: ≥10 mg/mL
创始人 Eli Lilly
储存温度 2-8℃
SMILES string COc1ccc(cc1)-c2oc3cc(OC)ccc3c2C(=O)c4ccc(cc4)C#N
InChI 1S/C24H17NO4/c1-27-18-9-7-17(8-10-18)24-22(20-12-11-19(28-2)13-21(20)29-24)23(26)16-5-3-15(14-25)4-6-16/h3-13H,1-2H3
InChI key RYNSGDFWBJWWSZ-UHFFFAOYSA-N

安全信息

象形图 GHS06
警示用语: Danger
危险声明 H301
预防措施声明 P301 + P310
危险分类 Acute Tox. 3 Oral
储存分类代码 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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