Longdaysin

半岛bd体育手机客户端 说明

应用

Longdaysin may be used to study cell signaling that regulate the circadian clock and behavior.

包装

5, 25 mg in glass bottle

生化/生理作用

Longdaysin inhibits CK1, ERK2, and CDK7 kinases in low mM concentrations. The activity of longdaysin results in a lengthening of circadian periods in cell based and in vivo systems. Transgenic zebrafish harboring a per3-luc reporter gene displayed a 10 hour lengthening of circadian period when treated with longdaysin. Longdaysin reduces the phosphorylation of PER1 the regulator of molecular clock function and manipulates the circadian clock.

基本信息

经验(实验)分子式	C16H16F3N5
分子量	335.33
MDL编号	MFCD20527323
PubChem化学物质编号	329825177

半岛bd体育手机客户端 性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to tan
溶解性	DMSO: ≥15 mg/mL
储存温度	2-8℃
SMILES string	CC(C)N(C=N1)C2=C1C(NCC3=CC(C(F)(F)F)=CC=C3)=NC=N2
InChI	1S/C16H16F3N5/c1-10(2)24-9-23-13-14(21-8-22-15(13)24)20-7-11-4-3-5-12(6-11)16(17,18)19/h3-6,8-10H,7H2,1-2H3,(H,20,21,22)
InChI key	REKSFCCYDQMSIN-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Danger
危险声明	H301 - H315 - H319 - H335 - H361d
预防措施声明	P202 - P261 - P264 - P301 + P310 - P302 + P352 - P305 + P351 + P338
危险分类	Acute Tox. 3 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable