半岛bd体育手机客户端 说明
生化/生理作用
ITE is an endogenous aryl hydrocarbon (Ah) receptor (AhR) agonist with broad-spectrum species reactivity and 5-fold higher potency than beta-naphthoflavone (by cell-based reporter assay). ITE upregulates CYP1A1/downregulates AhR in Hepa cells (0.1-5 μM), and induces fetus AhR activation in pregnant micein vivo(1.4mg ITE/mL DMSO/kg bw i.v. on gestation day/GD 14, fetal AhR activation assessed on GD15).
Endogenous ligand identified for aryl hydrocarbon receptor (AHR); ligand inducible transcription factor.
基本信息
| 经验(实验)分子式 | C14H10N2O3S |
| 分子量 | 286.31 |
| MDL编号 | MFCD06411597 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to beige |
| 溶解性 | DMSO: 2 mg/mL, clear |
| 储存温度 | 2-8℃ |
| SMILES string | COC(=O)c1csc(n1)C(=O)c2c[nH]c3ccccc23 |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H315 - H319 - H335 |
| 预防措施声明 | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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