半岛bd体育手机客户端 说明
应用
IMB-10 may be used to study integrin-mediated signaling in tumor cells.
包装
5, 25 mg in glass bottle
生化/生理作用
IMB-10 is a ligand for the αMβ2 integrin that stabilizes the binding of the integrin to endogenous ligands such as proMMP-9 and fibrinogen. IMB-10 blocks migration of lymphocyte cell lines and inhibits leukocyte infiltration in a murine thioglycolate-induced peritonitis.
IMB-10 is a thioxothiazolidine compound that inhibits the infiltration of leukocytes to the site of tumor and blocks the invasion of HSC-3 carcinoma. It modulates the host inflammatory responses and tumor progression.
基本信息
| 经验(实验)分子式 | C19H15NOS2 |
| 分子量 | 337.46 |
| MDL编号 | MFCD20134199 |
| PubChem化学物质编号 | 329825094 |
| NACRES | NA.77 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | yellow |
| 溶解性 | DMSO: ≥25 mg/mL |
| 储存温度 | 2-8℃ |
| SMILES string | Cc1ccccc1N2C(=S)S\C(=C\C=C\c3ccccc3)C2=O |
| InChI | 1S/C19H15NOS2/c1-14-8-5-6-12-16(14)20-18(21)17(23-19(20)22)13-7-11-15-9-3-2-4-10-15/h2-13H,1H3/b11-7+,17-13+ |
| InChI key | UYZLENPCNZVWQZ-QHMSGILQSA-N |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
Sigma-Aldrich
m.cnreagent.com
